Document Detail

Periodontal infection and adverse pregnancy outcomes: a systematic review of epidemiological studies.
MedLine Citation:
PMID:  16951876     Owner:  NLM     Status:  MEDLINE    
The objective of this systematic review was to evaluate analytical studies on periodontal disease as a possible risk factor for adverse pregnancy outcomes. A literature search of the MEDLINE, SciELO, and LILACS bibliographic databases and CAPES thesis database was conducted up to December 2005, covering epidemiological studies of periodontal disease and adverse pregnancy outcomes. Of the 964 papers identified, 36 analytical studies met the inclusion criteria. Twenty-six epidemiological studies reported associations between periodontal disease and adverse pregnancy outcomes. There was a clear heterogeneity between studies concerning measurement of periodontal disease and selection of type of adverse pregnancy outcome. Therefore no meta-analysis was performed. Most studies did not control for confounders, thus raising serious doubts about their conclusions. The methodological limitations of most studies did not allow conclusions concerning the effects of periodontal disease on adverse pregnancy outcomes. Larger and methodologically rigorous analytical studies using reliable outcomes and exposure measures are recommended.
Mario Vianna Vettore; Gabriela de Almeida Lamarca; Anna Thereza Thomé Leão; Filipe Brand Thomaz; Aubrey Sheiham; Maria do Carmo Leal
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Cadernos de saúde pública     Volume:  22     ISSN:  0102-311X     ISO Abbreviation:  Cad Saude Publica     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-04     Completed Date:  2007-05-03     Revised Date:  2013-03-18    
Medline Journal Info:
Nlm Unique ID:  8901573     Medline TA:  Cad Saude Publica     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  2041-53     Citation Subset:  IM    
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
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MeSH Terms
Brazil / epidemiology
Epidemiologic Studies
Fetal Membranes, Premature Rupture / epidemiology,  etiology*
Infant, Low Birth Weight*
Infant, Newborn
Periodontal Diseases / complications*,  epidemiology
Pregnancy Outcome / epidemiology*
Premature Birth / epidemiology,  etiology*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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