Document Detail


Periodic fever syndromes: a diagnostic challenge for the allergist.
MedLine Citation:
PMID:  17983370     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective was to present a case of periodic fever with aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), summarize the medical literature on PFAPA, review the differential diagnosis and suggest a diagnostic approach to periodic fevers in children. A PubMed search was conducted for all case reports and series of patients with PFAPA. The references of these papers yielded further case reports. Review articles or large case series were used for sources of information regarding the other periodic fever and autoinflammatory syndromes. All cases reported as PFAPA were included in the review, even though a few of the cases may not have been accurately diagnosed. The periodic fever and autoinflammatory syndromes of childhood are a group of diseases that cause repeated febrile illnesses with various associated symptoms. Except for PFAPA, each of these diseases is caused by a known genetic mutation. Effective treatment options and long-term prognosis varies among these syndromes. Children with periodic fever or autoinflammatory syndromes sometimes present to an Allergy/Immunology clinic for immunologic evaluation. It is important for the Allergy/Immunology specialist to be familiar with the clinical presentation, diagnostic approach and treatment of these conditions.
Authors:
M Lierl
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Allergy     Volume:  62     ISSN:  0105-4538     ISO Abbreviation:  Allergy     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-06     Completed Date:  2008-01-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804028     Medline TA:  Allergy     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  1349-58     Citation Subset:  IM    
Affiliation:
Cincinnati Children's Hospital Medical Center - Allergy and Immunology, Cincinnati, OH 41017, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Child, Preschool
Familial Mediterranean Fever / complications*,  diagnosis*,  therapy
Humans
Infant
Lymphadenitis / complications*,  diagnosis,  therapy
Male
Pharyngitis / complications*,  diagnosis,  therapy
Stomatitis, Aphthous / complications*,  diagnosis,  therapy
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical trial: effects of adefovir dipivoxil therapy in Asian and Caucasian patients with chronic h...
Next Document:  Quality-assessment of disease-specific quality of life questionnaires for rhinitis and rhinosinusiti...