Document Detail


Periodic fever and erythema nodosum associated with MDS with trisomy 8: report of two cases and review of the literature.
MedLine Citation:
PMID:  20376686     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
We report two cases of myelodysplastic syndrome (MDS) with trisomy 8 who had periodic fever and erythema nodosum (EN). A 74-year-old man showed periodic fever and EN. A diagnosis of MDS with trisomy 8 was made, and he was successfully treated with prednisolone (PSL). A 71-year-old man presented with intermittent fever, EN, and recurrent elevation of myogenic enzymes. Despite sustained inflammation, laboratory tests showed macrocytic anemia and thrombocytopenia. Marrow aspiration showed MDS with the chromosomal abnormality trisomy 8. He was successfully treated with PSL without repeated transient fever and elevation of creatine kinase. The results of a literature review of 35 cases of MDS with trisomy 8 and Behçet's disease-like symptoms, such as EN, oral ulcer and intestinal ulcer, suggest that the disease entity of "trisomy 8 syndrome" may be considered, and that it is an important differential diagnosis of periodic fever and EN.
Authors:
Takanori Fujimura; Naoichiro Yukawa; Ran Nakashima; Yoshitaka Imura; Daisuke Kawabata; Takaki Nojima; Koichiro Ohmura; Takao Fujii; Takashi Usui; Tsuneyo Mimori
Related Documents :
8523646 - Salmonella paratyphi a induced pancytopenia--a new association.
5834286 - Acute rheumatic fever in los angeles county.
19604446 - Visceral leishmaniasis and anti-tnf-alpha therapy: case report and review of the litera...
8920116 - A case study of an outbreak of african swine fever in spain.
20446076 - Bactrian ("double hump") acetaminophen pharmacokinetics: a case series and review of th...
7194436 - Hemichorea-hemiballism and lacunar infarction in the basal ganglia.
Publication Detail:
Type:  Journal Article     Date:  2010-04-08
Journal Detail:
Title:  Modern rheumatology / the Japan Rheumatism Association     Volume:  20     ISSN:  1439-7609     ISO Abbreviation:  Mod Rheumatol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100959226     Medline TA:  Mod Rheumatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  413-9     Citation Subset:  IM    
Affiliation:
Department of Rheumatology and Clinical Immunology, Kyoto University Hospital, Sakyo-ku, Kyoto, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Dermatomyositis complicated with hemorrhagic shock of the iliopsoas muscle on both sides and the thi...
Next Document:  Two cases of late-onset drug-induced lupus erythematosus caused by ticlopidine in elderly men.