Document Detail

Periodic fever as the only presenting symptom of multiple myeloma in a young man.
MedLine Citation:
PMID:  19036229     Owner:  NLM     Status:  MEDLINE    
We describe a 30-year-old male patient presenting with periodic fever. The patient underwent a series of laboratory tests, X-rays and CT scans. Quantitative immunoglobulin showed IgG 3210.00 mg/dl, IgA 20.00 mg/dl and IgM 27.70 mg/dl. Serum protein electrophoresis revealed a peak with a broad gamma band. Immunofixation revealed an immunoglobulin G -lambda monoclonal component. A bone marrow biopsy established the presence of multiple myeloma. To our knowledge, a periodic 24-hour-lasting fever as the only presenting symptom of multiple myeloma has never been reported.
C Trakatelli; E Kintiraki; J Koratzis; L Gamvrili; V Kotsis; M Sion
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Publication Detail:
Type:  Case Reports; Letter    
Journal Detail:
Title:  Journal of biological regulators and homeostatic agents     Volume:  22     ISSN:  0393-974X     ISO Abbreviation:  J. Biol. Regul. Homeost. Agents     Publication Date:    2008 Oct-Dec
Date Detail:
Created Date:  2008-11-27     Completed Date:  2009-02-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809253     Medline TA:  J Biol Regul Homeost Agents     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  263-5     Citation Subset:  IM    
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MeSH Terms
Fever / etiology*
Immunoglobulin G / blood
Immunoglobulin lambda-Chains / blood
Multiple Myeloma / complications*,  diagnosis*,  immunology
Reg. No./Substance:
0/Immunoglobulin G; 0/Immunoglobulin lambda-Chains

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