Document Detail

Periodic Eyelid Opening Associated with Burst-Suppression Electroencephalography due to Hypoxic Ischemic Injury.
MedLine Citation:
PMID:  22258894     Owner:  NLM     Status:  Publisher    
BACKGROUND: We report four patients who developed periodic eyelid opening following hypoxic ischemic injury. This manuscript reviews the clinical course of our patients as well as previously published cases and discusses the neuroanatomical basis of eyelid opening. METHODS: Data were collected from the patients' electronic medical record and digital electroencephalography recordings. RESULTS: In all patients, periodic eyelid opening was associated with a burst-suppression pattern on electroencephalography (EEG). Rapid eyelid opening appeared with the onset of bursts, while slow eyelid closure coincided with periods of suppression. Progressive rostrocaudal deterioration in brainstem function ensued, in each case culminating in brain death. CONCLUSIONS: Our experience and prior reports suggest that periodic eyelid opening following cardiac arrest is associated with a burst-suppression pattern on EEG. Since burst-suppression is highly (though not invariably) predictive of a poor outcome in this patient population, intensivists should be familiar with this neurological sign. Prospective studies are needed to define the neurophysiology of this phenomena and clarify its clinical significance.
Joseph M Ferrara; David J Houghton; Satish Rao
Related Documents :
2860044 - European cooperative crohn's disease study (eccds): clinical features and natural history.
23954454 - Autoantibodies to coagulation factors: from pathophysiology to diagnosis and therapy.
929104 - Amyloidosis and crohn's disease.
24165114 - Factors related to venous ulceration: a cross-sectional study.
22683424 - Circulating micrornas as candidate biomarkers in patients with systemic lupus erythemat...
21606824 - Gastroesophageal junction hyperplastic (inflammatory) polyps: a clinical and pathologic...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-19
Journal Detail:
Title:  Neurocritical care     Volume:  -     ISSN:  1556-0961     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101156086     Medline TA:  Neurocrit Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Neurology, Virginia Tech Carilion School of Medicine and Research Institute, 2 Riverside Cir, Roanoke, VA, 24016, USA,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The historical foundations of the research-practice distinction in bioethics.
Next Document:  Strategies beyond genome-wide association studies for atherosclerosis.