| Perinatal risk factors in preterm infants with moderate-to-profound hearing deficits. | |
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MedLine Citation:
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PMID: 3277017 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The perinatal histories of 16 preterm infants with confirmed moderate-to-profound hearing loss were examined to determine the perinatal factors that might have been associated with their abnormal auditory development. Of the 11 factors that were examined, eight factors occurred significantly more frequently in hearing-impaired infants when they were compared with 226 preterm infants who were cared for in the same intensive care unit in 1984. However, when the histories of the 16 infants with hearing loss were compared with those of 16 infants with normal hearing, who were matched according to gestational age, birthweight percentile and sex, there were no differences. The prevalence of aminoglycoside therapy was high in both groups of infants, but the mean duration of therapy in the infants with a hearing deficit was significantly longer (15 days compared with eight days; P less than 0.025). These observations suggest that younger, smaller, preterm infants with a complicated perinatal course and prolonged aminoglycoside therapy are at higher risk of auditory handicap. We recommend that the early identification of preterm infants with a hearing deficit should be achieved by recording brainstem auditory-evoked responses just before discharge from the intensive care unit. |
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Authors:
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A G Pettigrew; D A Edwards; D J Henderson-Smart |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: The Medical journal of Australia Volume: 148 ISSN: 0025-729X ISO Abbreviation: Med. J. Aust. Publication Date: 1988 Feb |
Date Detail:
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Created Date: 1988-03-17 Completed Date: 1988-03-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0400714 Medline TA: Med J Aust Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 174-7 Citation Subset: IM |
Affiliation:
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Department of Physiology, University of Sydney, NSW. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aminoglycosides
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adverse effects Anti-Bacterial Agents / adverse effects Evoked Potentials, Auditory Hearing Loss, Sensorineural / diagnosis, etiology* Humans Infant, Newborn Infant, Premature, Diseases / diagnosis, etiology* Retrospective Studies Risk Factors Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Aminoglycosides; 0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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