Document Detail

Perinatal risk factors for bronchopulmonary dysplasia in a national cohort of very low birth weight infants.
MedLine Citation:
PMID:  23178245     Owner:  NLM     Status:  Publisher    
OBJECTIVES: To assess the independent effect of perinatal factors on the risk for bronchopulmonary dysplasia (BPD) in very low birth weight (VLBW) infants. STUDY DESIGN: Population based observational study. Data was prospectively collected by the Israel Neonatal Network. Multivariable analyses identified independent risk factors for BPD. RESULTS: Of 12139 infants surviving to a post menstrual age of 36 weeks, 1,663 (13.7%) developed BPD. BPD was independently associated with young maternal age (OR 1.53), maternal hypertensive disorders (OR 1.28), antepartum hemorrhage (OR 1.26), male gender (OR 1.41), non-Jewish ethnicity (OR 1.23), birth defects (OR 1.94), small for gestational age (OR 2.65) and delivery room resuscitation (OR 1.86). Stratified analysis by gestational age groups showed that post-delivery resuscitation had a more pronounced effect with increasing maturity. CONCLUSIONS: Perinatal factors and pregnancy complications were independently associated with development of BPD in VLBW infants. Most risk factors identified were consistent within gestational age groups.
Gil Klinger; Nir Sokolover; Valentina Boyko; Lea Sirota; Liat Lerner-Geva; Brian Reichman;
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-21
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  -     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Mosby, Inc. All rights reserved.
Department of Neonatal Intensive Care, Schneider Children's Medical Center of Israel, Petah Tikva, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:
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