Document Detail

Perinatal profile of very low birthweight infants under a universal newborn hearing screening programme in a developing country: a case-control study.
MedLine Citation:
PMID:  20450464     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the perinatal profile and developmental risks of very low birth weight (VLBW) infants (<or=1500 g) under a universal hearing screening programme in a resource-poor country. METHODS: A case-control study of VLBW survivors matched by date of birth and sex with normal birth weight (>or=2500 g) infants delivered in an inner-city maternity hospital in Lagos, Nigeria. Hearing status was determined by two-stage screening with transient evoked otoacoustic emissions (TEOAE) followed by automated auditory brainstem response (AABR). Maternal and infant factors associated with VLBW were determined using unconditional and conditional multivariable logistic regression analyses. RESULTS: All 45 VLBW singletons (mean weight 1.3 +/- 0.1 kg) during the study period were matched with 225 controls (mean weight 3.4 +/- 0.5 kg). VLBW was associated with maternal occupation, lack of antenatal care, low 5-minute Apgar score and hyperbilirubinemia based on unmatched and matched analyses. Additionally, VLBW infants were significantly associated with failed or incomplete hearing screening outcomes. Four (10.5%) of the 38 infants tested with AABR failed, but none returned for diagnostic evaluation and one child had previously passed TEOAE. CONCLUSIONS: VLBW infants in resource-poor settings are associated with the risk of sensorineural hearing loss and other perinatal outcomes that may potentially compromise their optimal development in early childhood.
Bolajoko O Olusanya
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Developmental neurorehabilitation     Volume:  13     ISSN:  1751-8431     ISO Abbreviation:  Dev Neurorehabil     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-10     Completed Date:  2010-07-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101304394     Medline TA:  Dev Neurorehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  156-63     Citation Subset:  IM    
College of Medicine, University of Lagos, Maternal and Child Health Unit, Department of Community Health and Primary Care, Lagos, Nigeria.
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MeSH Terms
Case-Control Studies
Evoked Potentials, Auditory, Brain Stem / physiology*
Hearing Loss, Sensorineural / diagnosis*
Hearing Tests
Infant, Newborn
Infant, Very Low Birth Weight / physiology*
Neonatal Screening*
Odds Ratio
Otoacoustic Emissions, Spontaneous / physiology*
Program Evaluation
Regression Analysis
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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