Document Detail


Perinatal outcomes with the antepartum diagnosis of cystic hygroma.
MedLine Citation:
PMID:  15473217     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To describe antenatal diagnosis and clinical outcomes of fetal cystic hygroma. STUDY DESIGN: Retrospective case series derived from ultrasound database. Diagnoses were made from July 2000 through January 2003. RESULTS: Twenty-five fetuses were identified with cystic hygroma. Median gestational age at diagnosis was 17.3 weeks. Posterior nuchal cystic hygromas accounted for 21 (84%) cases, while two (8%) were axillary, and one each in the anterior neck and buttock. Additional abnormalities were noted in twenty (80%) fetuses; most common were non-immune hydrops (12/25, 48%) and cardiac defects (5/25, 20%). Eighteen patients (72%) underwent amniocentesis and ten were aneuploid. Six fetuses (25%) sustained intrauterine fetal demise and nine (38%) patients sought therapeutic termination. Nine infants (38%) were liveborn, but only six (25%) survived the neonatal period. CONCLUSIONS: Antenatal diagnosis of fetal cystic hygroma heralds an extremely poor perinatal prognosis. Associated abnormalities were noted in 80% of fetuses with a significant incidence of aneuploidy. Targeted ultrasonography and extensive counseling of parents is recommended.
Authors:
Carl H Rose; Mike Le; James A Bofill
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Mississippi State Medical Association     Volume:  45     ISSN:  0026-6396     ISO Abbreviation:  J Miss State Med Assoc     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-10-11     Completed Date:  2004-12-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505622     Medline TA:  J Miss State Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  259-62     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson 39216-4505, USA.
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MeSH Terms
Descriptor/Qualifier:
Chromosome Aberrations
Chromosome Disorders / genetics
Female
Fetal Diseases / genetics,  ultrasonography*
Head and Neck Neoplasms / genetics,  ultrasonography*
Humans
Lymphangioma, Cystic / genetics,  ultrasonography*
Lymphatic Abnormalities / complications,  ultrasonography*
Pregnancy
Retrospective Studies
Ultrasonography, Prenatal*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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