Document Detail


Perinatal outcome in an obstetric cohort of Mozambican women.
MedLine Citation:
PMID:  11245348     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective cohort of 908 consecutively enrolled pregnant women with biparietal diameter (DBP) compatible with gestational age equal to or below 21 weeks were followed up regularly at 2-4 weeks intervals. Normal antenatal care routine was applied. The newborns were followed until 7 days postpartum. The setting was two suburban antenatal clinics in Maputo and the delivery ward at the Maputo Central Hospital. The main outcome variables were low birth weight (LBW), preterm delivery, intrauterine fetal death, perinatal death and small for gestational age (SGA). For each of these variables the odds ratio for maternal risk factors was estimated with 95 per cent confidence interval and multiple logistic regression analysis was used. LBW occurred in 16.2 per cent and low maternal weight, low weight gain during pregnancy and not having a living child were risk factors. Prevalence of preterm birth was 15.4 per cent and low weight gain during pregnancy and malaria in the perinatal period were risk factors. Four per cent of mothers delivered stillborns and syphilis serology (positive VDRL test) was a risk factor. Perinatal death occurred in 4.7 per cent. These deaths were associated with being SGA, LBW or preterm at birth. Of the cohort women, 9.7 per cent delivered SGA newborns. It was concluded that maternal constitutional factors, particularly maternal weight gain, maternal height and maternal weight as well as syphilis and malaria during pregnancy, need to be given attention concerning the adverse outcomes addressed. The establishment of an obstetric cohort, followed prospectively, was possible in a low-income setting with limited numbers lost to follow-up at delivery.
Authors:
N B Osman; K Challis; M Cotiro; G Nordahl; S Bergström
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  47     ISSN:  0142-6338     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-03-13     Completed Date:  2001-04-05     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  England    
Other Details:
Languages:  eng     Pagination:  30-8     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, Eduardo Mondlane University, Central Hospital, Maputo, Mozambique. osman@teledata.mz
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Humans
Infant Mortality*
Infant, Low Birth Weight*
Infant, Newborn
Infant, Premature*
Mozambique / epidemiology
Odds Ratio
Pregnancy
Pregnancy Complications / epidemiology
Pregnancy Outcome*
Prospective Studies
Risk

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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