Document Detail


Perinatal outcome after ultrasound prenatal diagnosis of persistent right umbilical vein.
MedLine Citation:
PMID:  23317918     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: Our aim was to describe ultrasound findings and perinatal outcome after prenatal diagnosis of persistent right umbilical vein (PRUV). STUDY DESIGN: We performed a retrospective analysis of fetuses with an ultrasound-based prenatal diagnosis of PRUV on record at 2 tertiary centers in Madrid, Spain. We describe clinical, maternal, fetal and perinatal variables for all cases. RESULTS: A total of 20,426 fetuses were delivered between the study centers. We detected 22 cases (0.1%) of PRUV. The male-to-female ratio was 1:1. All cases were intrahepatic type and diagnosed during the second and third trimesters (median, 21 weeks; IQR, 20-29 weeks). Doppler ultrasound revealed normal flow in the ductus venosus in all cases. Nine fetuses (40.9%) had additional ultrasound anomalies but no chromosomal abnormalities. Cardiovascular malformations were the most frequently associated congenital anomalies (4/9), followed by neurological malformations (2/9). In 5 of the cases with no concomitant anomalies, the weight of the newborn was below the tenth percentile for gestational age. Gestational development was normal for the remaining newborns. Delivery was unremarkable, and post-natal evolution was favorable. CONCLUSION: Our results point to a potential association between PRUV and other fetal malformations and a very low rate of chromosomal abnormalities. Prenatal diagnosis of PRUV should be followed by detailed anatomical evaluation and echocardiography in order to rule out other structural malformations. The indication for a fetal karyotype study must be made on an individual basis considering PRUV type and other ultrasound findings.
Authors:
Raquel Martinez; Francisco Gamez; Coral Bravo; Pilar Sánchez; Carmen Orizales; Luis Ortiz; Juan De Leon-Luis
Related Documents :
23759108 - Does drug compliance change in asthmatic patients during pregnancy?
24281158 - A case of renal cell carcinoma with inferior vena cava tumor thrombus diagnosed during ...
23393708 - Pregnancy may aggravate arterial hypertension in women with takayasu arteritis.
23533318 - Pregnancy outcomes in hiv-infected women receiving long-term isoniazid prophylaxis for ...
9506208 - Type 2 cadherins in the human endometrium and placenta: their putative roles in human i...
3946488 - The relationship between abortion in the first pregnancy and development of pregnancy-i...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-11
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  -     ISSN:  1872-7654     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Fetal Medicine Unit, Department of Obstetrics and Gynecology, Hospital General Universitario Gregorio Marañón, Madrid, Spain; Department of Obstetrics and Gynecology, Hospital Universitario Severo Ochoa, Madrid, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Should HCV discordant couples with a seropositive male partner be treated with assisted reproduction...
Next Document:  Neutrophil gelatinase-associated lipocalin and interleukin-10 regulate intramacrophage Chlamydia pne...