Document Detail


Perinatal mortality in an English health region: geographical distribution and association with socio-economic factors.
MedLine Citation:
PMID:  9690262     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although the international and regional variability of perinatal mortality rates have been widely studied, less is known about the variability at the small-area level. The geographical distribution of perinatal mortality in the former North-West Thames Health Region, England, during 1981-90, and its association with small-area socio-economic factors, as measured by the Carstairs index of deprivation, were studied. Recently developed methods of analysis, including use of Bayesian statistics, were applied to obtain descriptive results and maps, and for fitting regression models that allowed for the presence of unmeasured risk factors. Significant heterogeneity (P < 0.001) of perinatal mortality across census wards and districts was found. The 5% of wards with the highest mortality experienced a risk more than 1.7 times that of the 5% with lowest mortality. Significant, positive association between deprivation and perinatal mortality was also found. Assuming causality, social differentials at the small-area level accounted for between 1.3% and 14.1% of all perinatal deaths, depending on which level of the Carstairs index was selected as reference. Although a proportion of such variability might be explained by social characteristics, a better understanding of the nature of the association is necessary.
Authors:
M Martuzzi; C Grundy; P Elliott
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Paediatric and perinatal epidemiology     Volume:  12     ISSN:  0269-5022     ISO Abbreviation:  Paediatr Perinat Epidemiol     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-10-05     Completed Date:  1998-10-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8709766     Medline TA:  Paediatr Perinat Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  263-76     Citation Subset:  IM    
Affiliation:
International Agency for Research on Cancer, Lyon, France.
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MeSH Terms
Descriptor/Qualifier:
England / epidemiology
Geography
Humans
Infant Mortality*
Infant, Newborn
Risk Factors
Socioeconomic Factors*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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