Document Detail

Perinatal development of human circadian rhythms: role of the foetal biological clock.
MedLine Citation:
PMID:  1528525     Owner:  NLM     Status:  MEDLINE    
The development of circadian rhythms and the neuronal mechanisms underlying their generation (particularly the suprachiasmatic nucleus of the hypothalamus) were reviewed. Based on perinatal animal studies and data from human foetuses and/or preterm infants it was concluded that human circadian rhythms are present as early as at 30 weeks of gestation. The significance of the mother and/or the environment regarding the entrainment of the "endogenous" foetal biological clock was emphasized.
M Mirmiran; J H Kok; K Boer; H Wolf
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neuroscience and biobehavioral reviews     Volume:  16     ISSN:  0149-7634     ISO Abbreviation:  Neurosci Biobehav Rev     Publication Date:  1992  
Date Detail:
Created Date:  1992-10-22     Completed Date:  1992-10-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806090     Medline TA:  Neurosci Biobehav Rev     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  371-8     Citation Subset:  IM    
Netherlands Institute for Brain Research, Amsterdam.
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MeSH Terms
Circadian Rhythm / physiology*
Embryonic and Fetal Development / physiology
Fetus / physiology*

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