Document Detail


Perinatal complications and long-term neurodevelopmental outcome of infants with intrauterine growth restriction.
MedLine Citation:
PMID:  23159694     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate perinatal and long-term complications of fetuses with intrauterine growth restriction (IUGR) compared to constitutionally small ones (SGA). STUDY DESIGN: Outcome of infants with IUGR and SGA born at the Medical University Graz, Austria between 2003 and 2009 was retrospectively analyzed. Group assignment was based on birth weight, Doppler ultrasound and placental morphology. Primary outcome was neurodevelopmental delay at two years corrected age. Secondary outcome were perinatal complications. RESULTS: We included 219 IUGR and 299 SGA infants for perinatal and 146 and 215 for long-term analysis. Fetuses with IUGR were delivered earlier (35vs.38 weeks) and had higher rates of mortality (8%vs.1%; OR 8.3) as well as perinatal complications (24.4%vs.1.0%, OR 31.6). Long-term outcome was affected by increased risk for neurodevelopmental impairment (24.7%vs.5.6%; OR 5.5) and growth delay (21.2%vs.7.4%, OR 3.4). CONCLUSION: IUGR infants are subject to an increased risk for adverse short- and long-term outcome compared to SGA children.
Authors:
Anne-Karen Von Beckerath; Martina Kollmann; Christa Rotky-Fast; Eva Karpf; Uwe Lang; Philipp Klaritsch
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-15
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  -     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Mosby, Inc. All rights reserved.
Affiliation:
Department of Obstetrics and Gynecology, Medical University of Graz, Austria.
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