Document Detail

Perinatal changes in adenine nucleotide content of developing rat kidney.
MedLine Citation:
PMID:  3701006     Owner:  NLM     Status:  MEDLINE    
Adenine nucleotides have been measured in fetal and newborn kidneys of rat using the luciferine-luciferase method. In fetuses, between days 18 and 21 of gestation there is a drop of the relative amount of ATP in the renal nucleotide pool. Consequently, the kidneys of 21 days-old fetuses have lowered ATP/ADP ratio (3.6) and energy charge (0.80) compared with values found on day 18 (6.9 and 0.91, respectively); this relative energy deficit is heightened in progesterone induced postmaturity. One hour after delivery whether the gestational stage is 21, 22 or 23 days, there is a rise in ATP and a decrease in AMP content which restore a high energy level in kidney of the newborn and a 30% increase in the total adenine nucleotide pool.
J Bastin; F Sofack; H Boulekbache; J Bismuth; J P Geloso
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of developmental physiology     Volume:  8     ISSN:  0141-9846     ISO Abbreviation:  J. Dev. Physiol.     Publication Date:  1986 Apr 
Date Detail:
Created Date:  1986-06-09     Completed Date:  1986-06-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7910737     Medline TA:  J Dev Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  97-103     Citation Subset:  IM    
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MeSH Terms
Adenine Nucleotides / analysis*
Adenosine Diphosphate / analysis
Adenosine Monophosphate / analysis
Adenosine Triphosphate / analysis
Animals, Newborn
Gestational Age
Kidney / analysis*,  growth & development
Rats, Inbred Strains
Reg. No./Substance:
0/Adenine Nucleotides; 56-65-5/Adenosine Triphosphate; 58-64-0/Adenosine Diphosphate; 61-19-8/Adenosine Monophosphate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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