Document Detail

Perinatal brain damage causation.
MedLine Citation:
PMID:  17762196     Owner:  NLM     Status:  MEDLINE    
The search for causes of perinatal brain damage needs a solid theoretical foundation. Current theory apparently does not offer a unanimously accepted view of what constitutes a cause, and how it can be identified. We discuss nine potential theoretical misconceptions: (1) too narrow a view of what is a cause (causal production vs. facilitation), (2) extrapolating from possibility to fact (potential vs. factual causation), (3) if X, then invariably Y (determinism vs. probabilism), (4) co-occurrence in individuals vs. association in populations, (5) one cause is all that is needed (single cause attribution vs. multicausal constellations), (6) drawing causal inferences from very small numbers of observations (the tendency to generalize), (7) unstated causal inferences, (8) ignoring heterogeneity, and (9) failing to consider alternative explanations for what is observed. We hope that our critical discussion will contribute to fruitful research and help reduce the burden of perinatal brain damage.
Olaf Dammann; Alan Leviton
Related Documents :
9467696 - Posture, spontaneous movements, and behavioural state organisation in infants affected ...
20004536 - Reduced cerebellar diameter in very preterm infants with abnormal general movements.
4040236 - Creatine kinase brain isoenzyme: relationship of cerebrospinal fluid concentration to t...
15325536 - Prenatal and postnatal steroid therapy and child neurodevelopment.
3975306 - Culture's influence in japanese and american maternal role perception and confidence.
16521676 - Multiple pregnancy in rural burkina faso: frequency, survival, and use of health services.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Developmental neuroscience     Volume:  29     ISSN:  1421-9859     ISO Abbreviation:  Dev. Neurosci.     Publication Date:  2007  
Date Detail:
Created Date:  2007-08-31     Completed Date:  2007-10-05     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  7809375     Medline TA:  Dev Neurosci     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  280-8     Citation Subset:  IM    
Copyright Information:
2007 S. Karger AG, Basel
Perinatal Infectious Disease Epidemiology Unit, OE 6415, Hannover Medical School, Hannover, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Abruptio Placentae / epidemiology,  physiopathology
Birth Injuries / epidemiology*,  physiopathology
Cerebral Hemorrhage, Traumatic / epidemiology,  physiopathology
Hypoxia, Brain / epidemiology*,  physiopathology
Infant, Newborn
Leukomalacia, Periventricular / epidemiology,  physiopathology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  pH nanoenvironment at the surface of single melanoma cells.
Next Document:  Serial diffusion tensor imaging detects white matter changes that correlate with motor outcome in pr...