Document Detail

Perinatal Epstein Barr virus infection in a premature infant.
MedLine Citation:
PMID:  10381227     Owner:  NLM     Status:  MEDLINE    
This is a case of an infant boy born at 28 weeks gestational age who presented on the 42nd day of life with hepatosplenomegaly, haemolytic anaemia, thrombocytopenia and atypical lymphocytes on the peripheral blood smear. He had an Epstein Barr virus (EBV) viral capsid antigen (VCA) IgM antibody titre of 1:160 and a positive test for heterophil antibodies. The cytomegalovirus (CMV) IgM titre was 0.600 and CMV IgG 70 Au/ml. The infant died 10 d later and the autopsy showed CMV inclusion bodies in the lungs, liver and kidneys. EBV infection acquired perinatally, probably co-existing with CMV, may have led to a fatal disease.
S Andronikou; A Kostoula; E Ioachim; S Dimou; A Ntourntoufi; S Papanikolaou
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Scandinavian journal of infectious diseases     Volume:  31     ISSN:  0036-5548     ISO Abbreviation:  Scand. J. Infect. Dis.     Publication Date:  1999  
Date Detail:
Created Date:  1999-07-29     Completed Date:  1999-07-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0215333     Medline TA:  Scand J Infect Dis     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  96-8     Citation Subset:  IM    
Neonatology Clinic, National Health Hospital of Ioannina, Greece.
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MeSH Terms
Antibodies, Viral / blood
Cytomegalovirus* / immunology,  isolation & purification
Cytomegalovirus Infections / complications
Fatal Outcome
Herpesviridae Infections / complications*
Herpesvirus 4, Human* / immunology,  isolation & purification
Immunoglobulin G / blood
Immunoglobulin M / blood
Infant, Newborn
Infant, Premature
Tumor Virus Infections / complications*
Reg. No./Substance:
0/Antibodies, Viral; 0/Immunoglobulin G; 0/Immunoglobulin M

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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