| Perifollicular vascularity in poor ovarian responders during IVF. | |
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MedLine Citation:
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PMID: 16488903 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Normal ovarian responders who have follicles with good vascularity shown by power Doppler scanning are associated with a better pregnancy rate following IVF treatment. This study evaluated the significance of perifollicular vascularity and follicular fluid hormonal profile in poor responders who developed < or = 3 dominant follicles. METHODS: Before oocyte retrieval, they underwent power Doppler examination for perifollicular vascularity. Patients who had all follicles with low-grade vascularity were classified as Group A, whereas those with at least one follicle with high-grade vascularity were Group B. Their follicular fluid concentrations of estradiol (E2), progesterone, HCG, vascular endothelial growth factor (VEGF) and inhibin B were measured. RESULTS: A total of 58 consecutive patients were recruited: 38 in Group A and 20 in Group B. Implantation rate, clinical pregnancy rate and follicular fluid hormonal concentrations were comparable for Groups A and B. Multiple pregnancy and live birth rates appeared higher, whereas miscarriage rate were lower in Group B than Group A, but these differences did not reach statistical significance. CONCLUSION: There were no significant differences in the implantation, clinical pregnancy and live birth rates among poor responders with and without high-grade perifollicular vascularity. |
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Authors:
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Anita Kan; Ernest Hung Yu Ng; William Shu Biu Yeung; Pak Chung Ho |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-02-17 |
Journal Detail:
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Title: Human reproduction (Oxford, England) Volume: 21 ISSN: 0268-1161 ISO Abbreviation: Hum. Reprod. Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-05-25 Completed Date: 2006-11-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8701199 Medline TA: Hum Reprod Country: England |
Other Details:
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Languages: eng Pagination: 1539-44 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, People's Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous Adult Estradiol / metabolism Female Fertilization in Vitro / methods* Follicular Fluid Humans Inhibins / metabolism Ovarian Follicle / blood supply, pathology* Ovary / blood supply, pathology* Pregnancy Pregnancy, Multiple Progesterone / metabolism Vascular Endothelial Growth Factor A / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Vascular Endothelial Growth Factor A; 0/inhibin B; 50-28-2/Estradiol; 57-83-0/Progesterone; 57285-09-3/Inhibins |
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