| Periepicardial fibrinolytic activity: relation to cardiac bleeding. | |
| | |
MedLine Citation:
|
PMID: 1154266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effects of various combinations of streptokinase-induced hyperfibrinolysis, electric shock, myocardial ischemia, and ventricular fibrillation on cat pericardial and epcardial fibrinolytic activity were studied. Streptokinase alone or electric shock alone slightly increased the periepicardial fibrinolytic activity but epicardial rebleeding did not occur. However, streptokinase infusions followed by electric shock and/or myocardial ischemia and/or ventricular fibrillation significantly incrased the periepicardial fibrinolytic activity and rebleeding of the epicardium occurred. Topical application of the fibrinolytic inhibitor epsilonaminocaproic acid (EACA) prevented the epicardial rebleeding. |
| | |
Authors:
|
G R Rhodes; D Silver |
Related Documents
:
|
19808416 - Sudden death and defibrillators in transposition of the great arteries with intra-atria... 16569556 - Restrictive physiology in cardiogenic shock: observations from echocardiography. 19576316 - Cardiogenic shock without flow-limiting angiographic coronary artery disease: (from the... 12688116 - Primary percutaneous transluminal coronary angioplasty in the acute infarction of the r... 18253156 - Targeted migration of mesenchymal stem cells modified with cxcr4 gene to infarcted myoc... 17267236 - Right ventricular outflow tract reconstruction for pulmonary regurgitation after repair... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Surgery Volume: 78 ISSN: 0039-6060 ISO Abbreviation: Surgery Publication Date: 1975 Aug |
Date Detail:
|
Created Date: 1975-11-07 Completed Date: 1975-11-07 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0417347 Medline TA: Surgery Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 230-7 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aminocaproic Acids
/
administration & dosage,
pharmacology Animals Blood Coagulation / drug effects Blood Coagulation Tests Cardiac Surgical Procedures* Cardiopulmonary Bypass Cats Electric Stimulation Fibrin / analysis, metabolism Fibrinogen / administration & dosage, pharmacology Fibrinolysis* / drug effects Heart Diseases* Hemorrhage* Injections, Intravenous Ischemia / chemically induced, metabolism Pericardium Postoperative Complications Streptokinase / administration & dosage, pharmacology Ventricular Fibrillation / metabolism |
| Chemical | |
Reg. No./Substance:
|
0/Aminocaproic Acids; 9001-31-4/Fibrin; 9001-32-5/Fibrinogen; EC 3.4.-/Streptokinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Adenomyomatosis of the gallbladder.
Next Document: A disposable in vivo oxygen electrode for the continuous measurement of arterial oxygen tension.