| Pericytes: blood-brain barrier safeguards against neurodegeneration? | |
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MedLine Citation:
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PMID: 21040834 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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The role of pericytes in the control of blood-brain barrier (BBB) integrity has remained enigmatic. In this issue, Bell et al. and two concurrent studies highlight that pericyte loss causes BBB breakdown and hypoperfusion. Remarkably, these vascular changes precede neurodegeneration and cognitive defects in old age. |
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Authors:
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Annelies Quaegebeur; Inmaculada Segura; Peter Carmeliet |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Neuron Volume: 68 ISSN: 1097-4199 ISO Abbreviation: Neuron Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-02 Completed Date: 2010-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8809320 Medline TA: Neuron Country: United States |
Other Details:
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Languages: eng Pagination: 321-3 Citation Subset: - |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Vesalius Research Center, KU Leuven, B-3000 Leuven, Belgium. |
Export Citation:
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Descriptor/Qualifier:
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| Comments/Corrections | |
Comment On:
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Neuron. 2010 Nov 4;68(3):409-27
[PMID:
21040844
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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