| Periconceptional folic acid supplementation as a social intervention. | |
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MedLine Citation:
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PMID: 8560289 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Periconceptional folic acid supplementation has been shown to decrease the first occurrence of isolated neural tube defects (NTDs) by as much as 50%, and to decrease the recurrence risk for NTDs by more than 70%. The possible mechanisms of vitamin supplementation in the prevention of NTDs are discussed, as are the current recommendations for reproductive-age women. Further, the limitations of dietary and pharmacological recommendations with regard to patient compliance as well as the possibility of grain fortification are reviewed. |
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Authors:
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N C Rose; M T Mennuti |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in perinatology Volume: 19 ISSN: 0146-0005 ISO Abbreviation: Semin. Perinatol. Publication Date: 1995 Aug |
Date Detail:
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Created Date: 1996-02-28 Completed Date: 1996-02-28 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 7801132 Medline TA: Semin Perinatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 243-54 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Diet* Female Folic Acid / administration & dosage*, physiology Humans Neural Tube Defects / embryology, etiology, prevention & control* |
| Chemical | |
Reg. No./Substance:
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59-30-3/Folic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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