| Pericentric inversion of chromosome 16 and eosinophilia in chronic myelomonocytic leukemia. | |
| | |
MedLine Citation:
|
PMID: 9109936 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report a case of myelodysplastic syndrome with bone marrow eosinophilia and the chromosomal abnormality, inv(16)(p13q22). Hematologic findings including monocytosis and trilineage myelodysplasia were consistent with chronic myelomonocytic leukemia, and numerous abnormal eosinophils were present in the bone marrow. Chromosomal analysis of all metaphase cells from peripheral blood and bone marrow revealed in(16)(p13q22), which is well known characteristic of acute myelomonocytic leukemia with eosinophilia (M4Eo). Both monocytes and eosinophils in this case may be derived from common leukemic progenitors affected by inv(16)(p13q22). |
| | |
Authors:
|
T Miyamoto; K Akashi; S Hayashi; A Oogami; T Okamura; H Iwasaki; M Murakawa; M Harada; Y Niho |
Related Documents
:
|
3471306 - Translocation between chromosomes 7 and 11 in nonlymphocytic neoplasia. 7497446 - Overexpression of the prad1 oncogene in a patient with prolymphocytic leukemia with t(1... 11520806 - Allelic loss on chromosome 4 (lyr2/tlsr5) is associated with myeloid, b-lympho-myeloid,... 17656256 - Cytogenetic and molecular study of the prdx4 gene in a t(x;18)(p22;q23): a cautionary t... 7792756 - Distribution of hla and haplotypes of colombian and jamaican black populations. 103316 - Chromosome studies in myelomatosis. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Cancer genetics and cytogenetics Volume: 94 ISSN: 0165-4608 ISO Abbreviation: Cancer Genet. Cytogenet. Publication Date: 1997 Apr |
Date Detail:
|
Created Date: 1997-05-01 Completed Date: 1997-05-01 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 7909240 Medline TA: Cancer Genet Cytogenet Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 99-102 Citation Subset: IM |
Affiliation:
|
Department of Hematology, Harasanshin General Hospital, Fukuoka, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Chromosome Aberrations / pathology* Chromosome Banding Chromosome Disorders Chromosome Inversion Chromosomes, Human, Pair 16* Eosinophilia / genetics* Humans Leukemia, Myelomonocytic, Chronic / genetics*, pathology Male |
| Comments/Corrections | |
Comment In:
|
Cancer Genet Cytogenet. 1998 Feb;101(1):81
[PMID:
9460508
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Involvement of the chromosomal region 11q13 in renal oncocytoma: case report and literature review.
Next Document: Detection of trisomy 8 using conventional cytogenetic techniques and interphase FISH analysis in 34 ...