Document Detail

Pericentric inversion (13) with two different recombinants in the same family.
MedLine Citation:
PMID:  7205907     Owner:  NLM     Status:  MEDLINE    
A family is described in which a pericentric inversion (13) was discovered in the father after the birth of an abnormal baby. In a further pregnancy amniocentesis was carried out. The fetal karyotype showed a rec(13)dup p,inv(13)(p11q22). The fetus's abnormalities were similar to those observed in the first child. Family studies showed that a first cousin, mentally retarded, had a rec(13)dup q,inv(13)(p11q22) karyotype. In this family, the risk of occurrence of a recombinant in offspring of an inversion carrier could be as high as 40%.
E M Williamson; J F Miller; M Seabright
Related Documents :
12632637 - Value of routine long bone radiographs in management of babies with a positive vdrl at ...
76807 - Adverse effects of routine procedures on preterm infants.
24119727 - Determinants of exclusive breastfeeding among mothers in ghana: a cross-sectional study.
3087297 - Central venous catheterisation in very low birthweight infants.
17052867 - Can tissue oxygenation index (toi) and cotside neurophysiological variables predict out...
17117997 - A longitudinal study of infant faecal microbiota during weaning.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of medical genetics     Volume:  17     ISSN:  0022-2593     ISO Abbreviation:  J. Med. Genet.     Publication Date:  1980 Aug 
Date Detail:
Created Date:  1981-05-13     Completed Date:  1981-05-13     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  2985087R     Medline TA:  J Med Genet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  309-12     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Abnormalities, Multiple / genetics
Chromosome Inversion*
Chromosomes, Human, 13-15 / ultrastructure*
Genetic Counseling
Infant, Newborn
Mental Retardation / genetics
Recombination, Genetic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Segregation of an X ring chromosome in two generations.
Next Document:  Prenatal diagnosis of a de novo non-fluorescent Y chromosome.