Document Detail

Pericarditis induced by high-dose cytosine arabinoside chemotherapy.
MedLine Citation:
PMID:  9322684     Owner:  NLM     Status:  MEDLINE    
Pericarditis is a rare side effect of chemotherapy. We report here the case of a patient treated with high-dose cytosine arabinoside (HD ara-c) who developed severe pericarditis. Interruption of HD ara-c and initiation of corticosteroid treatment were effective in resolving the pericardial effusion. This case illustrates this rare but potentially life-threatening cardiac complication of HD ara-c therapy as well as the beneficial effect of corticosteroid treatment.
C Hermans; N Straetmans; J L Michaux; A Ferrant
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of hematology     Volume:  75     ISSN:  0939-5555     ISO Abbreviation:  Ann. Hematol.     Publication Date:    1997 Jul-Aug
Date Detail:
Created Date:  1997-10-28     Completed Date:  1997-10-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9107334     Medline TA:  Ann Hematol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  55-7     Citation Subset:  IM    
Hematology Department, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, Brussels, Belgium.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Cytarabine / administration & dosage,  adverse effects*
Daunorubicin / administration & dosage
Leukemia, Myeloid, Acute / complications,  drug therapy,  radiotherapy
Methylprednisolone / therapeutic use
Mitoxantrone / administration & dosage
Pericarditis / chemically induced*,  complications,  drug therapy
Remission Induction
Reg. No./Substance:
147-94-4/Cytarabine; 20830-81-3/Daunorubicin; 65271-80-9/Mitoxantrone; 83-43-2/Methylprednisolone

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