| Pericardial tamponade. A presenting manifestation of procainamide-induced lupus erythematosus. | |
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MedLine Citation:
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PMID: 1124794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Procainamide, a frequently sued antiarrhythmic agent, may produce a syndrome clinically indistinguishable from idiopathic lupus erythematosis. Pericarditis with or without effusion is occasionally a prominent manifestation of the disease, but cardiac tamponade is exceptional. The patient described had a clinically evident and laboratory confirmed drug-induced syndrome complicated by an unusually severe pericarditis with effusion and tamponade necessitating pericardiocentesis. Treatment with prednisone produced impressive amelioration of the pericarditis with no recurrence of the lupus erythematosis syndrome during a prolonged period of observation following cessation of corticosteroid therapy. Prompt initation of steroid treatment in drug-induced lupus erythematosus complicated by massive pericardial effusion is strongly suggested by this experience. |
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Authors:
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M K Ghose |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of medicine Volume: 58 ISSN: 0002-9343 ISO Abbreviation: Am. J. Med. Publication Date: 1975 Apr |
Date Detail:
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Created Date: 1975-07-07 Completed Date: 1975-07-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0267200 Medline TA: Am J Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 581-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cardiac Tamponade / diagnosis, drug therapy, etiology* Humans Lupus Erythematosus, Systemic / chemically induced, complications* Male Pericardial Effusion / complications, radiography Pericarditis / etiology Prednisone / therapeutic use Procainamide / adverse effects* |
| Chemical | |
Reg. No./Substance:
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51-06-9/Procainamide; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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