Document Detail


Pericardial effusion with cardiac tamponade as a cardiac manifestation of Duchenne muscular dystrophy.
MedLine Citation:
PMID:  19623636     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Duchenne muscular dystrophy (DMD) is the most common hereditary neuromuscular disease in children. It is an X-linked hereditary dystrophinopathy due to the absence of dystrophin. Its onset is often in early childhood and presents with proximal distribution of weakness and a progressive course. Cardiac involvement in DMD is common, and its onset is usually after the age of 10 years. The most common cardiac manifestations are a dilated cardiomyopathy and cardiac arrhythmia. However, pericardial effusion with cardiac tamponade is a very rare cardiac complication of DMD. We report a boy with DMD who initially presented with progressive dyspnea and an enlarged cardiac silhouette on chest radiography who subsequently developed a large pericardial effusion with cardiac tamponade. Early recognition of pericardial effusion with cardiac tamponade is important for institution appropriate therapy.
Authors:
Jainn-Jim Lin; Mao-Sheng Hwang; Shao-Hsuan Hsia; Hung-Tao Chung; Yu-Sheng Chang; Kuang-Lin Lin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Muscle & nerve     Volume:  40     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-31     Completed Date:  2009-10-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  United States    
Other Details:
Languages:  eng     Pagination:  476-80     Citation Subset:  IM    
Affiliation:
Division of Pediatric Neurology, Department of Pediatrics, Chang Gung Children's Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Cardiac Tamponade / etiology*
Echocardiography / methods
Humans
Male
Muscular Dystrophy, Duchenne / complications*,  pathology
Myocardium / pathology*
Pericardial Effusion / etiology*
Tomography, X-Ray Computed / methods

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