Document Detail

Pericapillary fibrin cuff: a histological sign of venous leg ulceration.
MedLine Citation:
PMID:  2258474     Owner:  NLM     Status:  MEDLINE    
The incidence of pericapillary fibrin cuffs was investigated in 49 biopsies of venous leg ulcers and 67 biopsies of leg ulcers of non-venous etiology. Pericapillary fibrin cuffs were seen in 28 biopsies (57.1%) of venous leg ulcers, but only in 11 biopsies (16.4%) of non-venous leg ulcers. In the venous leg ulcers pericapillary fibrin cuffs occurred predominantly near the ulcer surface and around dilated capillaries. Dilation of the capillaries and inflammation probably contribute more to the pathogenesis of pericapillary fibrin cuffs than venous hypertension.
W Vanscheidt; H Laaff; H Wokalek; R Niedner; E Schöpf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cutaneous pathology     Volume:  17     ISSN:  0303-6987     ISO Abbreviation:  J. Cutan. Pathol.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1991-01-31     Completed Date:  1991-01-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0425124     Medline TA:  J Cutan Pathol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  266-8     Citation Subset:  IM    
Department of Dermatology, University of Freiburg, West Germany.
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MeSH Terms
Capillaries / pathology
Fibrin / analysis*
Leg Ulcer / etiology,  pathology*
Skin / blood supply,  chemistry*
Varicose Ulcer / pathology*
Reg. No./Substance:

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