Document Detail

Periarticular calcinosis associated with anti-Jo-1 antibodies sine myositis. Expanding the clinical spectrum of the antisynthetase syndrome.
MedLine Citation:
PMID:  11409138     Owner:  NLM     Status:  MEDLINE    
We describe a 58-year-old woman who developed interstitial lung disease (ILD), polyarthritis, and anti-Jo-1 antibodies, with no clinical evidence of myositis. Despite successful treatment with corticosteroid and azathioprine for her arthritis and pulmonary condition, she developed deforming arthropathy of the hands, with periarticular calcinosis. The association of anti-Jo-1 antibodies, ILD, and periarticular calcinosis with subluxing arthropathy sine myositis is rare, with few cases reported. This report expands the clinical spectrum of the antisynthetase syndrome, which is broader than previously reported.
R Queiro-Silva; I Bañegil; J R de Dios-Jiménez de Aberásturi; J Belzunegui-Otano; C González-Beneitez; M Figueroa-Pedrosa
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  28     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-06-18     Completed Date:  2001-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  1401-4     Citation Subset:  IM    
Rheumatology Service, Complejo Hospitalario Donostia, and Rheumatology Unit, Hospital de Mendaro, San Sebastian-Guipúzcoa, Spain.
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MeSH Terms
Antibodies, Antinuclear / blood*
Calcinosis / immunology*,  pathology
Cervical Vertebrae / pathology
Hand Dermatoses / immunology,  pathology
Ligases / immunology*
Pulmonary Fibrosis / immunology*,  pathology
Wrist Joint / pathology
Reg. No./Substance:
0/Antibodies, Antinuclear; 0/Jo-1 antibody; EC 6.-/Ligases

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