Document Detail

Perianeurysm edema with second-generation bioactive coils.
MedLine Citation:
PMID:  17976696     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Perianeurysm edema is an uncommon complication of intracranial aneurysms, occurring mostly in giant aneurysms that suddenly thrombose. CASE DESCRIPTION: We present the first report of an unruptured, nongiant, saccular aneurysm that developed marked perianeurysm edema after embolization with Matrix2 coils. In this case, follow-up catheter angiography showed a new coil tail protruding beyond the dome of the aneurysm in the region of the most intense edema. CONCLUSIONS: We postulate that perianeurysm edema may occur after breakdown of the aneurysm wall accompanied by an inflammatory response to exposed bioactive coils. Clinicians should be aware of this potential complication and consider performing earlier surveillance angiography when this occurs to ensure that there has not been a shift in the coil mass and recurrence of the aneurysm.
Franklin A Marden; Christopher M Putman
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-10-31
Journal Detail:
Title:  Surgical neurology     Volume:  69     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-19     Completed Date:  2008-07-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  627-32; discussion 632     Citation Subset:  IM    
Division of Interventional Neuroradiology, Department of Radiology, Inova Fairfax Hospital, Falls Church, VA 22042, USA.
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MeSH Terms
Biocompatible Materials / adverse effects*
Brain Edema / etiology*,  radiography,  therapy
Embolization, Therapeutic / adverse effects*,  instrumentation*
Intracranial Aneurysm / therapy*
Lactic Acid / adverse effects*
Polyglycolic Acid / adverse effects*
Reg. No./Substance:
0/Biocompatible Materials; 0/polylactic acid-polyglycolic acid copolymer; 26009-03-0/Polyglycolic Acid; 50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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