Document Detail

Perianal granular cell tumor: report of a case and review of the literature.
MedLine Citation:
PMID:  19856672     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Granular cell tumor was first described by Abrikossoff in 1926. Over the years several cases of this neoplasm have been reported, with a variety of localizations. We here report a case of perianal granular cell tumor and discuss its histogenesis and its relevance to clinical practice. METHODS: The clinical course and histopathology of the case are reviewed, and a literature search for other reported cases has been performed. RESULTS: A 46-year-old woman presented with a perianal nodular lesion. Pathological examination revealed a granular cell tumor. A literature search produced only 25 other cases of anal and perianal granular cell tumors. CONCLUSIONS: Granular cell tumors are rarely observed in the perianal region. Their existence must always be borne in mind in the differential diagnosis of perianal neoplasms. In most cases surgical excision is curative, but potential malignant transformation must be considered during therapeutic procedures and follow-up.
Massimiliano Mistrangelo; Paola Cassoni; Gitana Scozzari; Isabella Castellano; Giorgia Gavello; Franco Corno; Mario Morino
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Tumori     Volume:  95     ISSN:  0300-8916     ISO Abbreviation:  Tumori     Publication Date:    2009 Jul-Aug
Date Detail:
Created Date:  2009-10-27     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0111356     Medline TA:  Tumori     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  538-41     Citation Subset:  IM    
Department of Surgery and Center of Minimal Invasive Surgery, University of Turin, Italy.
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MeSH Terms
Anus Neoplasms / pathology*,  surgery
Granular Cell Tumor / pathology,  surgery
Middle Aged

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