| Periampullary diverticula and technical success of endoscopic retrograde cholangiopancreatography. | |
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MedLine Citation:
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PMID: 18818967 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION/AIM: Periampullary diverticula (PAD) discovered incidentally during endoscopic retrograde cholangiopancreatography are usually asymptomatic, but can be a source of significant morbidity. The size of the diverticula and position of the papilla in relation to the diverticula are variable. The twofold aim of this study was to determine the prevalence of PAD in adult Indian patients and technical success of endoscopic retrograde cholangiopancreatography (ERCP). METHODS: Patients with PAD (group I) were prospectively entered into a database from May 2006 to May 2007. Diverticula were categorized based on size into small (<1.5 cm) and large (>1.5 cm). Papilla was arbitrarily defined as type A when located outside the diverticulum and type B when the position was intradiverticular. Requirement of needle knife papillotomy (NKP), sphincterotomy, and overall success/failure of the procedure were recorded. One hundred consecutive patients without PAD undergoing ERCP served as controls (group II). RESULTS: PAD were present in 46 (7.5%) of the 600 patients undergoing ERCP for various indications (group I). Mean age of patients with PAD (51 +/- 15 years) was significantly higher than control group (39 +/- 17 years) (p < 0.001). Of the 46 diverticula, 26 diverticula (56.5%) were large. In small diverticula, the papilla was extradiverticular (type A) in all 20 (100%) patients, whereas in the group with diverticula >1.5 cm only 57% was extradiverticular. Successful cannulation was achieved in 97% (45/46). NKP was done in six patients, five of whom had type A papilla. There was a significant high rate of NKP inpatients without PAD compared with patients with PAD (p = 0.001), whereas the rate of endoscopic papillotomy (EPT) was similar in both groups. Complete common bile duct (CBD) clearance was achieved in 93% patients in PAD group as compared with 96% in the non-PAD group (p = nonsignificant). Complications after ERCP were similar in both groups. CONCLUSION: PAD were present in 7.5% of patients. Fifty-six percent of PAD were large and in the vast majority (76%) papilla was extradiverticular in location. PAD were not associated with an increased risk of EPT-related complications. |
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Authors:
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Pankaj Tyagi; Praveen Sharma; Barjesh Chander Sharma; A S Puri |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2008-09-26 |
Journal Detail:
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Title: Surgical endoscopy Volume: 23 ISSN: 1432-2218 ISO Abbreviation: Surg Endosc Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-05-27 Completed Date: 2009-08-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8806653 Medline TA: Surg Endosc Country: Germany |
Other Details:
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Languages: eng Pagination: 1342-5 Citation Subset: IM |
Affiliation:
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Department of Gastroenterology, G.B. Pant Hospital, Room No 211, Academic Block, New Delhi, 110002, India. drpankajtyagi@rediffmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Ampulla of Vater Child Child, Preschool Cholangiopancreatography, Endoscopic Retrograde / methods* Diverticulum / diagnosis, epidemiology, surgery* Duodenal Diseases / diagnosis, epidemiology, surgery* Female Follow-Up Studies Humans India / epidemiology Male Middle Aged Prevalence Prospective Studies Sphincterotomy, Endoscopic / methods* Treatment Outcome Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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