Document Detail

Peri-threshold encoding of stimulus frequency and intensity in the M100 latency.
MedLine Citation:
PMID:  9592054     Owner:  NLM     Status:  MEDLINE    
Recent work has suggested that, in addition to spatial tonotopy, pitch and timbre information may be encoded in the temporal activity of the auditory cortex. Specifically, the post-stimulus latency of the maximal cortical evoked neuromagnetic field (M100 or N1m) is a function of stimulus frequency. We investigated the additional effect of varying the stimulus intensity on the M100 response. A 37-channel biomagnetometer recorded neuromagnetic fields over the temporal lobe of healthy volunteers in response to monaurally presented tones. The frequency dependence of the M100 latency remained remarkably invariant even at low stimulus intensity. Thus, for peri-threshold stimuli, frequency information appears encoded in the temporal form of the evoked response.
S M Stufflebeam; D Poeppel; H A Rowley; T P Roberts
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroreport     Volume:  9     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-07-08     Completed Date:  1998-07-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  91-4     Citation Subset:  IM    
Department of Radiology, University of California, San Francisco, 94143, USA.
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MeSH Terms
Acoustic Stimulation
Analysis of Variance
Auditory Threshold
Evoked Potentials, Auditory / physiology*
Reaction Time / physiology*
Reference Values

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