| Peri-operative silent myocardial ischaemia in patients undergoing lower limb joint replacement surgery: an indicator of postoperative morbidity or mortality? | |
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MedLine Citation:
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PMID: 10364858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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One hundred and twenty-seven patients undergoing major lower limb joint replacement surgery were studied to determine the incidence of silent myocardial ischemia and to ascertain any link between pre-operative cardiac risk factors, silent myocardial ischaemia and postoperative morbidity. Patients underwent ambulatory ECG monitoring for 4 days (on the pre-operative night and for 3 days postoperatively). Postoperative cardiorespiratory symptomatology and morbidity was assessed by questionnaire at 3 months. Eighty-seven patients had risk factors for silent myocardial ischaemia; 42 patients (30 with risk factors) had peri-operative silent myocardial ischaemia. The median ischaemic loads (range) were 1.04 (0.32-13.31) min.h-1 pre-operatively and 5.53 (0.26-56.39), 6.69 (0.04-42.71) and 1.23 (0.1-53.74) min.h-1 on postoperative days 1-3, respectively. Risk factors did not predict the occurrence of silent myocardial ischaemia or an increased ischaemic load pre-operatively or overall postoperatively. New symptoms (chest pain, palpitations, breathlessness or fatigue) were associated with both silent myocardial ischaemia and ischaemic load (p < 0.05). Thus cardiac risk factors do not predict the occurrence of silent myocardial ischaemia or adverse outcome. Peri-operative silent myocardial ischaemia was associated with increased postoperative fatigue. |
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Authors:
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G W French; W H Lam; Z Rashid; J W Sear; P Foëx; S Howell |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Anaesthesia Volume: 54 ISSN: 0003-2409 ISO Abbreviation: Anaesthesia Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-06-23 Completed Date: 1999-06-23 Revised Date: 2009-09-29 |
Medline Journal Info:
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Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 235-40 Citation Subset: AIM; IM |
Affiliation:
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Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headington, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Arthroplasty, Replacement* Electrocardiography, Ambulatory Fatigue / etiology Female Follow-Up Studies Humans Leg / surgery* Male Middle Aged Myocardial Ischemia / etiology* Postoperative Complications* Risk Factors Treatment Outcome |
| Grant Support | |
ID/Acronym/Agency:
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//Wellcome Trust |
| Comments/Corrections | |
Comment In:
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Anaesthesia. 1999 Aug;54(8):817
[PMID:
10460545
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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