Document Detail


Peri-infarct ischemia determined by cardiovascular magnetic resonance evaluation of myocardial viability and stress perfusion predicts future cardiovascular events in patients with severe ischemic cardiomyopathy.
MedLine Citation:
PMID:  17060098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: We assessed whether cardiovascular magnetic resonance imaging (CMR) of peri-infarct ischemia provides prognostic information in severe ischemic cardiomyopathy (ICM) patients referred for revascularization. METHODS: Twenty-one patients with severe ICM were recruited prospectively for combined stress adenosine perfusion, late gadolinium enhancement, and rest perfusion studies. The patients were followed for in-hospital and post-discharge cardiovascular events. RESULTS: During 12+/- 9.8 months follow-up, 67% of the patients with peri-infarct ischemia and 13% of the patients without peri-infarct ischemia had cardiovascular events (p = 0.03). CONCLUSION. In severe ICM patients, the presence of peri-infarct ischemia was associated with a higher incidence of cardiovascular events.
Authors:
Miwako Tsukiji; Patricia Nguyen; Girish Narayan; Jeffrey Hellinger; Frandics Chan; Robert Herfkens; John M Pauly; Michael V McConnell; Phillip C Yang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance     Volume:  8     ISSN:  1097-6647     ISO Abbreviation:  J Cardiovasc Magn Reson     Publication Date:  2006  
Date Detail:
Created Date:  2006-10-24     Completed Date:  2007-02-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815616     Medline TA:  J Cardiovasc Magn Reson     Country:  United States    
Other Details:
Languages:  eng     Pagination:  773-9     Citation Subset:  IM    
Affiliation:
Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, California, USA.
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MeSH Terms
Descriptor/Qualifier:
Adenosine / diagnostic use
Adult
Aged
Cardiomyopathies / pathology
Contrast Media
Coronary Circulation*
Female
Gadolinium DTPA / diagnostic use
Humans
Magnetic Resonance Imaging, Cine*
Male
Middle Aged
Myocardial Infarction / pathology*
Myocardial Ischemia / pathology*
Myocardium / pathology
Prognosis
Prospective Studies
Vasodilator Agents / diagnostic use
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Vasodilator Agents; 58-61-7/Adenosine; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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