Document Detail


Perfusion thallium imaging of type I diabetes patients with end stage renal disease: comparison of oral and intravenous dipyridamole administration.
MedLine Citation:
PMID:  2315467     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eighty patients with type I diabetes and end stage renal disease were prospectively evaluated for coronary artery disease with dipyridamole-thallium-201 scintigraphy and quantitative coronary angiography. Forty patients received dipyridamole orally, and 40 received it intravenously. The prevalence of coronary artery disease was 53%. There were no significant differences in the accuracy of the two dipyridamole tests (sensitivity = 85%, specificity = 85%, accuracy = 85% for the oral group; sensitivity = 86%, specificity = 72%, accuracy = 79% for the intravenous group). Combining the 80 patients into a single group gave a sensitivity of 86%, a specificity of 79%, and an accuracy of 83% for the detection of coronary disease. Although the accuracy of this test in this patient population was similar to that previously reported for other groups, the prevalence of disease was high and resulted in a low predictive value of a negative test (83%).
Authors:
R J Boudreau; J T Strony; R P duCret; C C Kuni; Y Wang; R F Wilson; J S Schwartz; W R Castaneda-Zuniga
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Radiology     Volume:  175     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-04-25     Completed Date:  1990-04-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  103-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, University of Minnesota Hospital and Clinics, Minneapolis 55455.
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adult
Aged
Coronary Angiography
Coronary Disease / etiology,  radiography,  radionuclide imaging*
Diabetes Mellitus, Type 1 / complications,  radionuclide imaging*
Dipyridamole / administration & dosage,  diagnostic use*
Female
Humans
Injections, Intravenous
Kidney Failure, Chronic / complications*
Male
Middle Aged
Thallium Radioisotopes / diagnostic use*
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes; 58-32-2/Dipyridamole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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