Document Detail


Perfusion of rabbit hearts with human blood results in immediate graft thrombosis, a temporally distinct component of hyperacute rejection.
MedLine Citation:
PMID:  14621807     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hyperacute discordant xenograft rejection can be simulated by a blood-perfused working isolated heart. The survival of the heart is dependent on its functional integrity, and the preparation is thus sensitive to early myocardial damage. Perfusion of rabbit hearts with human blood produces immediate graft destruction by a thrombotic process which is a distinct component of hyperacute rejection.
Authors:
J Forty; R Hasan; N Cary; D J White; J Wallwork
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transplant international : official journal of the European Society for Organ Transplantation     Volume:  5 Suppl 1     ISSN:  0934-0874     ISO Abbreviation:  Transpl. Int.     Publication Date:  1992  
Date Detail:
Created Date:  2003-11-18     Completed Date:  2003-12-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8908516     Medline TA:  Transpl Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  S305-6     Citation Subset:  IM    
Affiliation:
Papworth Hospital, Cambridge, UK.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Animals
Coronary Thrombosis / etiology
Heart Transplantation / adverse effects,  pathology*
Humans
Perfusion
Rabbits
Transplantation, Heterologous / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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