| Perfusion magnetic resonance imaging and magnetic resonance spectroscopy of cerebral gliomas showing imperceptible contrast enhancement on conventional magnetic resonance imaging. | |
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MedLine Citation:
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PMID: 15344981 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of the present paper was to evaluate the utility of perfusion MRI in cerebral gliomas showing imperceptible contrast enhancement on conventional MRI, and to evaluate the relationships of perfusion MRI and magnetic resonance (MR) spectroscopic results in these tumours. Twenty-two patients with histopathologically proven cerebral gliomas and showing insignificant contrast enhancement on conventional MR were included in the present study. All patients underwent perfusion MRI and MR spectroscopy on a 1.5-T MR system. Significant differences of the relative cerebral blood volume (rCBV) values and the choline : creatine ratios were noted between low-grade and anaplastic gliomas (P < 0.01). Good correlation was found between the rCBV values and the choline : creatine values (y = 0. 532x + 1.5643; r = 0.67). Perfusion MRI can be a useful tool in assessing the histopathological grade of non-contrast-enhancing cerebral gliomas. Along with MR spectroscopic imaging it can serve as an important technique for preoperative characterization of such gliomas, so that accurate targeting by stereotactic biopsies is possible. |
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Authors:
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A Batra; R P Tripathi; A K Singh |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Australasian radiology Volume: 48 ISSN: 0004-8461 ISO Abbreviation: Australas Radiol Publication Date: 2004 Sep |
Date Detail:
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Created Date: 2004-09-03 Completed Date: 2005-02-10 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0047441 Medline TA: Australas Radiol Country: Australia |
Other Details:
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Languages: eng Pagination: 324-32 Citation Subset: IM |
Affiliation:
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NMR Research Centre, Institute Of Nuclear Medicine and Allied Sciences, Defence Research and Development Organization, SK Mazumdar Road, Timarpur, Delhi-110054, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Volume Brain / metabolism, physiopathology Choline / metabolism Creatine / metabolism Female Glioma / diagnosis*, physiopathology, surgery Humans Magnetic Resonance Angiography* Magnetic Resonance Spectroscopy Male Middle Aged Supratentorial Neoplasms / diagnosis*, physiopathology, surgery |
| Chemical | |
Reg. No./Substance:
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57-00-1/Creatine; 62-49-7/Choline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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