| Perfusion abnormalities in hemimegalencephaly. | |
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MedLine Citation:
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PMID: 19809940 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Cerebrovascular changes are rarely discussed in patients with hemimegalencephaly. These alterations have previously been associated with epileptical activity. CASE: We report the case of a 36-week gestation neonate presenting with total right hemimegalencephaly, as demonstrated by a magnetic resonance imaging (MRI) performed in the first days of life. Perfusion-weighted imaging displayed a clear hypervascularization of the right hemisphere. Diffusion-tensor imaging showed an arrangement of white matter fibers concentrically around the ventricle on the right hemisphere. AngioMRI showed an obvious asymmetry in the size of the middle cerebral arteries, with the right middle cerebral artery being prominent. The baby was free of clinical seizures during his first week of life. An electroencephalogram at that time displayed an asymmetric background activity, but no electrical seizures. CONCLUSION: Perfusion anomalies in hemimegalencephaly may not necessarily be related to epileptical activity, but may be related to vessel alterations. |
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Authors:
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P Wintermark; E Roulet-Perez; M Maeder-Ingvar; A C Moessinger; F Gudinchet; R Meuli |
Publication Detail:
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Type: Journal Article Date: 2009-10-06 |
Journal Detail:
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Title: Neuropediatrics Volume: 40 ISSN: 1439-1899 ISO Abbreviation: Neuropediatrics Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-10-07 Completed Date: 2009-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8101187 Medline TA: Neuropediatrics Country: Germany |
Other Details:
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Languages: eng Pagination: 92-6 Citation Subset: IM |
Copyright Information:
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(c) Georg Thieme Verlag KG Stuttgart, New York. |
Affiliation:
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Division of Neonatology, Department of Pediatrics, University Hospital (CHUV) and Lausanne Medical School, Lausanne, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Arterial Diseases
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diagnosis*,
etiology* Diffusion Magnetic Resonance Imaging / methods Electroencephalography / methods Humans Image Processing, Computer-Assisted / methods Infant Magnetic Resonance Angiography / methods Magnetic Resonance Imaging / methods Male Malformations of Cortical Development / complications* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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