| Perfusion CT scanning and CT angiography in the evaluation of extracranial-intracranial bypass grafts. | |
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MedLine Citation:
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PMID: 20617876 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Object Extracranial-intracranial (EC-IC) bypass surgery remains an important treatment alternative for patients with occlusive cerebrovascular disease. The aim of the present study was to use perfusion CT and CT angiography (CTA) to evaluate cerebral hemodynamics and bypass patency in patients with occlusive cerebrovascular disease before and after EC-IC bypass surgery. Methods Ten patients underwent perfusion CT and CTA before and after bypass surgery. Preoperative and postoperative digital subtraction angiography served as the diagnostic gold standard. An artery bypass was established from the superficial temporal artery to a cortical branch of the middle cerebral artery. Perfusion CT scanning was performed at the level of the basal ganglia. Color-coded perfusion maps of cerebral blood volume, cerebral blood flow, and time to peak were calculated. Results Preoperative perfusion CT showed significant prolonged time to peak and reduced cerebral blood flow of the affected hemisphere. Postoperative neurological deterioration did not develop in any patient. Computed tomography angiography provided adequate evaluation of the anastomoses as well as the course and caliber of the bypass and confirmed bypass patency in all patients. Postoperative perfusion CT showed improved cerebral hemodynamics with a return to nearly normal perfusion parameters. Conclusions Computed tomography angiography is a noninvasive and reliable tool for evaluating patients with EC-IC bypass. Perfusion CT allows monitoring of hemodynamic changes after bypass surgery. The combination of both modalities enables noninvasive anatomical and functional analysis of superficial temporal artery-middle cerebral artery anastomoses using a single CT protocol. Hemodynamic evaluation of patients with occlusive cerebrovascular disease before and after surgery may improve the prediction of outcome and may help identify patients in whom a bypass procedure can be performed. |
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Authors:
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Soenke Langner; Steffen Fleck; Rebecca Seipel; Henry W S Schroeder; Norbert Hosten; Michael Kirsch |
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Publication Detail:
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Type: Journal Article Date: 2010-07-09 |
Journal Detail:
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Title: Journal of neurosurgery Volume: 114 ISSN: 1933-0693 ISO Abbreviation: J. Neurosurg. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0253357 Medline TA: J Neurosurg Country: United States |
Other Details:
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Languages: eng Pagination: 978-83 Citation Subset: AIM; IM |
Affiliation:
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Institute for Diagnostic Radiology and Neuroradiology, and. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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