| Performing functional magnetic resonance imaging in patients with Parkinson's disease treated with deep brain stimulation. | |
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MedLine Citation:
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PMID: 16671094 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Deep brain stimulation (DBS) is a relatively novel treatment in advanced Parkinson's disease (PD). Functional magnetic resonance imaging (fMRI) is a useful technique for examining the effects of DBS both within the basal ganglia and its cortical connectivity. There are technical difficulties in imaging patients with PD, and the DBS itself can generate image artifacts. We describe aspects related to optimizing the fMRI acquisition parameters in patients with DBS and the results of sensorimotor activation tasks performed by four PD patients during hand, foot, and tongue movements, both before and after DBS implant. Provided that all safety conditions are followed, it is possible to perform fMRI in patients with PD and DBS. The standard DBS surgical procedure has to be slightly modified in order to reduce image artifacts. The event-related design provided increased power to detect sensorimotor cortex and basal ganglia activation. |
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Authors:
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Paula R Arantes; Ellison F Cardoso; Maria A Barreiros; Manoel J Teixeira; Márcia R Gonçalves; Egberto R Barbosa; Sukhi Shergill Sukwinder; Claudia C Leite; Edson Amaro |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Movement disorders : official journal of the Movement Disorder Society Volume: 21 ISSN: 0885-3185 ISO Abbreviation: Mov. Disord. Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-08-30 Completed Date: 2007-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610688 Medline TA: Mov Disord Country: United States |
Other Details:
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Languages: eng Pagination: 1154-62 Citation Subset: IM |
Copyright Information:
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(c) 2006 Movement Disorder Society |
Affiliation:
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Department of Radiology, University of São Paulo Medical School, São Paulo, Brazil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Artifacts Brain / pathology Deep Brain Stimulation* Disease Progression Functional Laterality Humans Magnetic Resonance Imaging / methods* Male Middle Aged Motor Activity Oxygen / blood Parkinson Disease / physiopathology*, therapy* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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