| Performance of third trimester ultrasound for the prediction of the small for gestational age fetus and evaluation of contingency screening policies. | |
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MedLine Citation:
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PMID: 21858886 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the performance of third trimester fetal biometry and fetal Doppler studies for the prediction of small for gestational age (SGA ≤ 5(th) centile of local charts) neonate. To explore contingency strategies using a first trimester prediction model based on maternal and fetal parameters and third trimester ultrasound. METHODS: Observational cross sectional study. Fetal biometry and umbilical artery and middle cerebral artery Doppler studies were performed routinely in uncomplicated pregnancies at 30-34 weeks. RESULTS: Abdominal circumference (AC, AUC = 0.85) and ultrasound estimated fetal weight (EFW, AUC = 0.87) were equally good predictors of SGA. The addition of umbilical artery Doppler, smoking status and first trimester indices (f-βhCG and PAPP-A MoM) improved marginally the model (AUC = 0.88) but the difference was not statistically significant. A contingency strategy of rescanning in the third trimester 50% of the population according to the risk estimation by a first trimester prediction model yields a detection rate of 79% for 25% screen positive rate. CONCLUSIONS: Third trimester ultrasound is effective in screening for SGA in uncomplicated pregnancies. The use of a contingency screening policy can reduce the need for unnecessary examinations. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd. |
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Authors:
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A P Souka; I Papastefanou; A Pilalis; V Michalitsi; D Kassanos |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-8-19 |
Journal Detail:
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Title: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology Volume: - ISSN: 1469-0705 ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-8-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9108340 Medline TA: Ultrasound Obstet Gynecol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd. |
Affiliation:
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Fetal Medicine Unit, 3rd Department of Obstetrics and Gynaecology, University of Athens, 'Attikon' University Hospital, Athens, Greece; Leto Maternity Hospital, Fetal Medicine Unit, Athens, Greece. athena.souka@googlemail.com. |
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