| Performance of a new cardiac cryoablation system in the treatment of cavotricuspid valve isthmus-dependent atrial flutter. | |
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MedLine Citation:
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PMID: 15683482 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We sought to evaluate prospectively the safety and efficacy of cryothermal energy to ablate typical atrial flutter (AFL). Ablation of cardiac tissue using cryothermal energy has recently been developed as an alternative to radiofrequency energy, which may offer certain advantages in the treatment of AFL. This prospective, multicenter nonrandomized study of a new catheter-based system for the treatment of cavotricuspid isthmus (CTI)-dependent AFL enrolled patients between 18 and 75 years of age. The CTI dependence of AFL was confirmed at electrophysiologic study with activation mapping and/or entrainment. Patients with atrial septal defect, recent myocardial infarction, left ventricular ejection fraction <0.30, or prior AFL ablation were excluded. Cryoablation of AFL was performed in 48 patients from 11 centers. The procedure was immediately successful in 45 patients (94%), and effective in 30 of 40 patients with complete data available at 6 months. Cryoablation is a promising new treatment of CTI-dependent AFL refractory to medical therapy. Further improvements in catheter design and intravascular sheaths will be tested in a larger multicenter trial. |
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Authors:
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James P Daubert; Robert H Hoyt; Roy John; Larry Chinitz; David T Martin; Christopher Fellows; Gregory Feld; William Pelkey; Ruchir Sehra; |
Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 28 Suppl 1 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-02-01 Completed Date: 2005-06-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: S142-5 Citation Subset: IM |
Affiliation:
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Cardiology Unit, Department of Medicine, University of Rochester Medical Center, Rochester, New York 14642-8679, USA. James_Daubert@URMC.Rochester.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Atrial Flutter
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etiology,
surgery* Catheter Ablation* / instrumentation Cryosurgery* / instrumentation Female Humans Male Middle Aged Prospective Studies Tricuspid Valve Vena Cava, Inferior |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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