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Performance of dual source versus 256-slice multi-slice CT in the evaluation of 16 coronary artery stents.
MedLine Citation:
PMID:  23280306     Owner:  NLM     Status:  Publisher    
INTRODUCTION: Invasive coronary angiography is the reference method for identification of in-stent restenosis (ISR) bearing the disadvantages of high costs and invasiveness. New approaches like dual-source CT (DSCT) and 256-multi-slice CT (256-MSCT) may potentially be the future methods of choice to reliably exclude ISR in patients with low or intermediate risk of restenosis. We sought to compare the performance of DSCT and 256-MSCT for the in vitro assessment of stent lumen diameter and basic scan parameters in stents of various diameters and designs. MATERIALS AND METHODS: In 16 coronary artery stents we evaluated relative in-stent lumen diameter, attenuation, noise, attenuation-/signal-to-noise ratio (ANR/SNR) and radiation dose (CTDI(vol)) in an acknowledged coronary vessel in vitro phantom (iodine-filled plastic tubes) with DSCT (Siemens, SOMATOM Definition, collimation=2×64×0.6mm, pitch=0.26, current=400mAs/rot, voltage=120kV, tube-rotation-time=330ms) and 256-MSCT (Philips Brilliance, iCT, tube collimation=2×128×0.625mm, pitch=0.18, current=800mAs(eff), voltage=120kV, tube-rotation-time=270ms). Diameter analysis was conducted with the observer-independent full-width-at-half-maximum (FWHM) technique. RESULTS: DSCT and 256-MSCT revealed similar stent lumen diameters (50.7±7.2% vs. 50.8±7.4%, p=0.98). Attenuation (-19±25HU vs. 54±29HU), ANR (-0.9±1.2 vs. 2.9±1.8) and SNR (12.1±2.4 vs. 17.4±1.9) were better in the DSCT (all p<0.001) at the expense of significantly higher radiation doses (CTDI(vol)=87 vs. 51mGy, p<0.01). Noise was comparable (21±2HU vs. 20±2HU, p=n.s.). Only stents with a diameter >3mm allowed sufficient stent lumen assessment in both scanners and showed a relative lumen diameter of 60-66%. CONCLUSIONS: The measured stent lumen diameter and image noise were similar in both scanners. Yet the DSCT offered a more truthful stent lumen visualization at the cost of higher radiation dose. Applying the FWHM approach only stents with a diameter >3mm offered sufficient stent lumen assessment.
Florian André; Grigorios Korosoglou; Waldemar Hosch; Evangelos Giannitsis; Hans-Ulrich Kauczor; Hugo A Katus; Henning Steen
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-29
Journal Detail:
Title:  European journal of radiology     Volume:  -     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-1-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
University of Heidelberg, Department of Cardiology, Im Neuenheimer Feld 410, Heidelberg, 69120, Germany. Electronic address:
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