Document Detail

Performance of Self-Reported Measures for Periodontitis in Rheumatoid Arthritis and Osteoarthritis.
MedLine Citation:
PMID:  25269524     Owner:  NLM     Status:  Publisher    
Objective: To evaluate the performance of self-report against the reference standard of clinically-defined periodontitis in rheumatoid arthritis (RA) and osteoarthritis (OA) patients after accounting for factors associated with periodontitis. Methods: Six self-report periodontitis questions were evaluated in RA and OA patients. Questions were validated against a reference standard of severe and moderate-to-severe periodontitis based on full-mouth examination. Multivariable logistic regression was used to evaluate the performance of: 1) self-report alone; 2) age, sex, education, and smoking status; and 3) a combination of the above. Model performance was assessed using the c-statistic. Convergent validity of self-reported 'bone loss/deep pockets' and 'loose teeth' was assessed; associations of self-report with RA disease characteristics were explored. Results: Self-report performed similarly in RA and OA, with individual specificity for periodontitis ≥ 68% and sensitivity between 9.8% and 45%. Question-only models yielded c-statistics of 0.66-0.72 while risk factor-only models yielded c-statistics of 0.74-0.79. The highest performing models incorporated both self-report questions and periodontitis risk factors with c-statistics ≥ 0.79. Greater radiographic alveolar bone loss was observed among participants reporting 'bone loss or deep pockets' (p < 0.001) and 'loose teeth' (p < 0.001). Among RA patients, 'loose teeth', but not other self-report items, was associated with rheumatoid factor positivity (p = 0.047) and higher disease activity (p < 0.001). Conclusion: Patient self-report, when combined with other risk factors, performs well in identifying periodontitis among patients with RA and OA. Self-report questions related to alveolar bone loss exhibit excellent convergent validity in these patient subsets.
Brian W Coburn; Harlan R Sayles; Jeffrey B Payne; Robert S Redman; Jeffery C Markt; Mark W Beatty; Garth R Griffiths; David J McGowan; Ted R Mikuls
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-30
Journal Detail:
Title:  Journal of periodontology     Volume:  -     ISSN:  1943-3670     ISO Abbreviation:  J. Periodontol.     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-10-1     Completed Date:  -     Revised Date:  2014-10-2    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-17     Citation Subset:  -    
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