| Performance measurements of the Siemens mMR integrated whole-body PET/MR scanner. | |
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MedLine Citation:
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PMID: 22080447 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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METHODS: The NEMA NU 2-2007 protocol was followed for studying the PET performance. The following measurements were performed: spatial resolution; scatter fraction, count losses, and randoms; sensitivity; accuracy of the correction for count losses and randoms; and image quality. The quality control manual of the American College of Radiology was followed for studying the MR performance. The following measurements were performed: geometric accuracy, spatial resolution, low-contrast detectability, signal-to-noise ratio, static field (B(0)) homogeneity, radiofrequency field (B(1)) homogeneity, and radiofrequency noise. RESULTS: An average spatial resolution of 4.3 mm in full width at half maximum was measured at 1 cm offset from the center of the field of view. The system sensitivity was 15.0 kcps/MBq along the center of the scanner. The scatter fraction was 37.9%, and the peak noise-equivalent count rate was 184 kcps at 23.1 kBq/mL. The maximum absolute value of the relative count rate error due to dead-time losses and randoms was 5.5%. The average residual error in scatter and attenuation correction was 12.1%. All MR parameters were within the tolerances defined by the American College of Radiology. B(0) inhomogeneities below 1 ppm were measured in a 120-mm radius. B(1) homogeneity and signal-to-noise ratio were equivalent to those of a standard MR scanner. No radiofrequency interference was detected. CONCLUSION: These results compare favorably with other state-of-the-art PET/CT and PET/MR scanners, indicating that the integration of the PET detectors in the MR scanner and their operation within the magnetic field do not have a perceptible impact on the overall performance. The MR subsystem performs essentially like a standalone system. However, further work is necessary to evaluate the more advanced MR applications, such as functional imaging and spectroscopy. |
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Authors:
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Gaspar Delso; Sebastian Fürst; Björn Jakoby; Ralf Ladebeck; Carl Ganter; Stephan G Nekolla; Markus Schwaiger; Sibylle I Ziegler |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2011-11-11 |
Journal Detail:
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Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine Volume: 52 ISSN: 1535-5667 ISO Abbreviation: J. Nucl. Med. Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-06 Completed Date: 2012-01-31 Revised Date: 2012-04-11 |
Medline Journal Info:
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Nlm Unique ID: 0217410 Medline TA: J Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 1914-22 Citation Subset: IM |
Affiliation:
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Nuklearmedizin, Klinikum Rechts der Isar, Technische Universität München, München, Germany. gaspar.delso@tum.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Humans Magnetic Phenomena Magnetic Resonance Imaging / instrumentation, methods*, standards Male Positron-Emission Tomography / instrumentation, methods*, standards Prostatic Neoplasms / radionuclide imaging Quality Control Radio Waves Scattering, Radiation Sensitivity and Specificity Systems Integration* Whole Body Imaging / instrumentation, methods*, standards |
| Comments/Corrections | |
Erratum In:
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J Nucl Med. 2012 Mar;53(3):507 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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