| Performance of integrated FDG-PET/contrast-enhanced CT in the diagnosis of recurrent pancreatic cancer: comparison with integrated FDG-PET/non-contrast-enhanced CT and enhanced CT. | |
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MedLine Citation:
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PMID: 19949988 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this study is to evaluate the accuracy of 2-deoxy-2-[F-18]fluoro-D: -glucose-positron emission tomography (FDG-PET)/computed tomography (CT) with intravenous contrast for depiction of recurrent pancreatic cancer, compared with PET/non-enhanced CT and CT. PROCEDURE: Forty-five patients previously treated for pancreatic cancer underwent PET/CT for suspected recurrence. Lesion status was determined on the basis of histopathology and radiological imaging follow-up. RESULTS: Patient-based analysis showed that sensitivity, specificity, and accuracy of PET/contrast-enhanced CT were 91.7%, 95.2%, and 93.3%, respectively, whereas those of PET/non-enhanced CT were 83.3%, 90.5%, and 86.7%, respectively, and those of enhanced CT were 66.7%, 85.7%, and 75.6%, respectively. In 21 patients whom the final diagnosis was obtained from the histopathologic examination, those figures of PET/contrast-enhanced CT were 94.7%, 50.0%, and 90.4%, respectively. The sensitivity of PET/contrast-enhanced CT in detecting local recurrence, abdominal lymph node metastasis, and peritoneal dissemination were 83.3%, 87.5%, and 83.3%, respectively. CONCLUSION: PET/contrast-enhanced CT is an accurate modality for assessing recurrence of pancreatic cancer. |
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Authors:
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Kazuhiro Kitajima; Koji Murakami; Erena Yamasaki; Yasushi Kaji; Mitsugi Shimoda; Keiichi Kubota; Narufumi Suganuma; Kazuro Sugimura |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-12-01 |
Journal Detail:
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Title: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Volume: 12 ISSN: 1860-2002 ISO Abbreviation: Mol Imaging Biol Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-02 Completed Date: 2010-11-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101125610 Medline TA: Mol Imaging Biol Country: United States |
Other Details:
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Languages: eng Pagination: 452-9 Citation Subset: IM |
Affiliation:
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Department of Radiology, Dokkyo University School of Medicine, Mibu, Japan. kazu10041976@yahoo.co.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Contrast Media / diagnostic use* Female Fluorodeoxyglucose F18 / diagnostic use* Humans Lymphatic Metastasis / radiography, radionuclide imaging Male Middle Aged Organ Specificity Pancreatic Neoplasms / pathology, radiography*, radionuclide imaging*, surgery Positron-Emission Tomography* Recurrence Tomography, X-Ray Computed* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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