| Performance of FASTPlaqueTB and a modified protocol in a high HIV prevalence community in South Africa. | |
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MedLine Citation:
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PMID: 19460258 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Modifications in the FASTPlaqueTB test protocol have resulted in an increase in the analytical limits of detection. This study investigated whether the performance of a modified prototype was able to increase the detection of smear-negative, culture-positive sputum samples as compared to the first generation FASTPlaqueTB test. Modifications to the FASTPlaqueTB did result in increased detection of smear-negative samples, but this was associated with a decrease in the specificity of the test. Before the FASTPlaqueTB can be considered as a viable replacement for smear microscopy and culture for the identification of tuberculosis, further work is required to resolve the performance issues identified in this study. |
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Authors:
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André P Trollip; H Albert; R Mole; T Marshall; G van Cutsem; D Coetzee |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Volume: 13 ISSN: 1027-3719 ISO Abbreviation: Int. J. Tuberc. Lung Dis. Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-05-22 Completed Date: 2009-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9706389 Medline TA: Int J Tuberc Lung Dis Country: France |
Other Details:
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Languages: eng Pagination: 791-3 Citation Subset: IM |
Affiliation:
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Biotec Laboratories South Africa Ltd, Cape Town, South Africa. andre.trollip@bioteclabs.co.za |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Comorbidity HIV Infections / epidemiology* Humans Microbial Sensitivity Tests / methods* Predictive Value of Tests South Africa / epidemiology Sputum / microbiology Tuberculosis, Pulmonary / diagnosis*, epidemiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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