| Performance considerations of prosthetic actuators for round-window stimulation. | |
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MedLine Citation:
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PMID: 19941946 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Round-window (RW) stimulation has improved speech perception in patients with mixed hearing loss. In cadaveric temporal bones, we recently showed that RW stimulation with an active prosthesis produced differential pressure across the cochlear partition (a measure related to cochlear transduction) similar to normal forward sound stimulation above 1 kHz, when contact area between the prosthesis and RW is secured. However, there is large variability in the hearing improvement in patients implanted with existing modified prosthesis. This is likely because the middle-ear prosthesis used for RW stimulation was designed for a very different application. In this paper, we utilize recently developed experimental techniques that allow for the calculation of performance specifications for a RW actuator. In cadaveric human temporal bones (N=3), we simultaneously measure scala vestibuli and scala tympani intracochlear pressures, as well as stapes velocity and ear-canal pressure, during normal forward sound stimulation as well as reverse RW stimulation. We then calculate specifications such as the impedance the actuator will need to oppose at the RW, the force with which it must push against the RW, and the velocity and distance by which it must move the RW to obtain cochlear stimulation equivalent to that of specific levels of ear-canal pressure under normal sound stimulation. This information is essential for adapting existing prostheses and for designing new actuators specifically for RW stimulation. |
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Authors:
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Hideko Heidi Nakajima; Saumil N Merchant; John J Rosowski |
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Publication Detail:
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Type: Evaluation Studies; In Vitro; Journal Article; Research Support, N.I.H., Extramural Date: 2009-11-23 |
Journal Detail:
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Title: Hearing research Volume: 263 ISSN: 1878-5891 ISO Abbreviation: Hear. Res. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-10 Completed Date: 2010-08-20 Revised Date: 2011-07-28 |
Medline Journal Info:
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Nlm Unique ID: 7900445 Medline TA: Hear Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 114-9 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2009 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Otology and Laryngology, Harvard Medical School, Boston, MA 02115, USA. heidi_nakajima@meei.harvard.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acoustic Impedance Tests Acoustic Stimulation Cadaver Cochlea / physiopathology Hearing Aids* Hearing Loss, Mixed Conductive-Sensorineural / drug therapy, physiopathology Humans Ossicular Prosthesis* Pressure Round Window, Ear / physiopathology* Transducers |
| Grant Support | |
ID/Acronym/Agency:
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R01 DC004798-09/DC/NIDCD NIH HHS; R01 DC04798/DC/NIDCD NIH HHS; T32 DC00020/DC/NIDCD NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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