Document Detail


Perforation of the terminal ileum with cytomegalovirus vasculitis and Kaposi's sarcoma in a patient with acquired immunodeficiency syndrome.
MedLine Citation:
PMID:  2820074     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This case report documents a perforation of the terminal ileum in a 40-year-old white male homosexual with the acquired immunodeficiency syndrome. The perforation occurred at a site that had severe cytomegalovirus infection and was in close proximity to multiple nodules of Kaposi's sarcoma. The ileum showed multiple deep ulcers with large numbers of cytomegalovirus inclusions and vasculitis with infected endothelial cells, small-vessel thrombosis, focal disruption, and hemorrhage. We review the evidence that cytomegalovirus infection--and not Kaposi's sarcoma--was responsible for this perforation and, in light of the new medical therapy for such infections, should be regarded as an important cause of gastrointestinal perforation in patients with the acquired immunodeficiency syndrome.
Authors:
G Burke; L Nichols; K Balogh; S Hammer; W Jensen; F Pomposelli; R Jenkins
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Surgery     Volume:  102     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1987-10-02     Completed Date:  1987-10-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  540-5     Citation Subset:  AIM; IM; X    
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MeSH Terms
Descriptor/Qualifier:
Acquired Immunodeficiency Syndrome / complications*,  pathology
Adult
Cytomegalovirus Infections / complications*,  pathology
Humans
Ileal Diseases / complications*,  pathology
Ileal Neoplasms / complications*,  pathology
Intestinal Perforation / complications*,  pathology
Male
Sarcoma, Kaposi / complications*,  pathology
Vasculitis / complications*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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