| Perforated pseudomembranous colitis in the breast-fed infant. | |
| | |
MedLine Citation:
|
PMID: 1501036 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Pseudomembranous colitis (PMC) is uncommon in the infant and complications requiring surgical intervention are rare. All prior cases have involved the direct administration of antibiotics to the child. A 2-month-old girl required bowel resection for perforation of a thickened and inflamed left colon. Findings were consistent with PMC and the stool was Clostridium difficile toxin positive. The patient was treated with vancomycin and did well. The patient's mother later admitted to self-administration of ciprofloxacin while breast-feeding her infant. Oral doses of this drug are concentrated in breast milk at levels higher than serum. Antibiotics derived from breast milk can cause complicated PMC in the infant. A directed history can establish an early diagnosis and help distinguish PMC from other more common infantile enterocolitides. |
| | |
Authors:
|
T Harmon; G Burkhart; H Applebaum |
Related Documents
:
|
20401426 - Complementary feeding: inappropriate practices in infants. 2741856 - Risk factors for infant botulism in the united states. 7271286 - Breast development in the newborn. 871666 - May mothers given warfarin breast-feed their infants? 15732596 - Toxoplasmosis in nilgais (boselaphus tragocamelus) and a saiga antelope (saiga tatarica). 3960626 - Polysorbate 80 and e-ferol toxicity. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of pediatric surgery Volume: 27 ISSN: 0022-3468 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 1992 Jun |
Date Detail:
|
Created Date: 1992-09-17 Completed Date: 1992-09-17 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 744-6 Citation Subset: IM |
Affiliation:
|
Department of Surgery, Kaiser Foundation Hospital, Los Angeles, CA. 90027. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Breast Feeding* Ciprofloxacin / adverse effects Enterocolitis, Pseudomembranous / etiology* Female Humans Infant Intestinal Perforation / etiology* Milk, Human / chemistry |
| Chemical | |
Reg. No./Substance:
|
85721-33-1/Ciprofloxacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Treatment for necrotizing enterocolitis perforation in the extremely premature infant (weighing less...
Next Document: Microperforation of a duodenal diaphragm as a cause of paradoxical gas in congenital duodenal obstru...